The White House Office of Science and Technology Policy (OSTP) revealed a request for information (RFI) on Nov. 26, 2025, in search of enter from academia, non-public sector trade teams and different related stakeholders on federal insurance policies “aim[ed] to accelerate the American scientific enterprise, enable groundbreaking discoveries, and ensure that scientific progress and technological innovation benefit all Americans.” The RFI signifies that responses will “inform the formulation of Executive branch efforts to advance and maintain U.S [science and technology] leadership.”
The RFI discusses the nation’s historical past of scientific innovation and dominance throughout industries starting from healthcare to the house program. It additionally discusses intensifying international competitors and developments in rising and quickly creating areas of analysis, reminiscent of synthetic intelligence (AI) and quantum info science.
In the RFI, OSTP takes the place that “new scientific opportunities, intensifying global competition, and evidence that traditional approaches to research could be greatly improved” necessitate a “comprehensive assessment of how the Federal government prioritizes and structures scientific research.”
OSTP invitations RFI respondents to handle an inventory of analysis policy-related questions, together with, however not restricted to, the next:
- What coverage modifications to federal funding mechanisms, procurement processes or partnership authorities would allow stronger public-private collaboration and permit America to faucet into its huge non-public sector to raised drive use-inspired primary and early-stage utilized analysis?
- How can federal packages higher determine and develop scientific expertise throughout the nation, significantly leveraging digital instruments and distributed analysis fashions to have interaction researchers exterior of conventional tutorial facilities?
- What insurance policies would encourage the formation and scaling of regional innovation ecosystems that join native companies, universities, academic establishments and the native workforce – significantly in areas the place the federal authorities has current analysis property reminiscent of nationwide laboratories or federally funded analysis facilities?
- How can the federal authorities strengthen analysis safety to guard delicate applied sciences and dual-use analysis whereas minimizing compliance burdens on researchers?
- How can the federal authorities leverage and put together for advances in AI techniques that will remodel scientific analysis – together with automated speculation era, experimental design, literature synthesis and autonomous experimentation? What infrastructure investments, organizational fashions and workforce improvement methods are wanted to comprehend these capabilities whereas sustaining scientific rigor and analysis integrity?
- How can the federal authorities foster nearer collaboration amongst scientists, engineers and expert technical staff and higher combine coaching pathways, recognizing that breakthrough analysis typically requires deep collaboration between theoretical and utilized experience?
Arguably one of the vital vital questions invitations respondents to determine particular federal statutes, laws or insurance policies that “create unnecessary barriers to scientific research or the deployment of research outcomes[.]” OSTP asks respondents to “describe the barrier, its impact on scientific progress, and potential remedies that would preserve legitimate policy objectives while enabling innovation.”
The RFI remark interval closes at 11:59 p.m. ET on Dec. 26, 2025.
If you’ve questions or want help, Holland & Knight’s Clinical Research Team could be completely happy to help.