The lives of tens of millions of individuals throughout the Middle East – and the destiny of the world economic system – will hinge on the final result of make-or-break talks between the US and Iran this weekend in Pakistan.

The streets of the capital Islamabad have been emptied by a sudden two-day public vacation, declared to implement strict safety for the arrival of the American and Iranian delegations for his or her first talks since the starting of the warfare.

A fragile two-week ceasefire that paved the means for the talks is holding for now. But Israel’s large lethal bombardment of Hezbollah and disagreements over whether or not Lebanon is included in the truce, might nonetheless derail the conferences.

Here’s what we know:

The talks between Iran and the United States are set to begin Saturday morning native time in Islamabad, in accordance to the White House.

The US delegation might be led by Vice President JD Vance, particular envoy Steve Witkoff, and Jared Kushner, President Donald Trump’s son in legislation.

US Special Envoy Steve Witkoff (L) delivers a press conference with Jared Kushner at the Elysee Palace in Paris on January 6, 2026.

Tehran has not formally introduced its delegation, however some native media studies say it will likely be led by the speaker of Iran’s Parliament, Mohammad Bagher Ghalibaf. A regime insider with a fame for suppressing dissent, Ghalibaf has emerged as a key interlocutor with the Trump administration all through the warfare. Many of Iran’s leaders have been killed by US-Israeli strikes in current weeks.

Given each side can’t seem to agree about what’s in the ceasefire, aligning on the agenda for the talks could also be tough.

Trump has cited “a 10-point proposal from Iran,” which he referred to as “a workable basis on which to negotiate.”

But then Iran began sharing a 10-point list that included calls for the US might by no means agree to, resembling acknowledging its management over the Strait of Hormuz and reparations for warfare damages and the lifting of all sanctions. Other variations printed on state media additionally included recognizing the nation’s proper to nuclear enrichment.

White House press secretary Karoline Leavitt mentioned Trump had been referring to a distinct 10-point plan that was “more reasonable.”

Meanwhile Trump and his workforce have their very own 15-point proposal. That plan has not been revealed in full however is claimed to embody Iran committing to no nuclear weapons, handing over its extremely enriched uranium, limits on Tehran’s protection capabilities, and the reopening of the Strait of Hormuz.

A key query now’s whether or not the talks will produce some kind of center floor – or whether or not they are going to collapse and restart a warfare that has already wrought destruction throughout components of the Middle East and sparked a historic world oil disaster.

Lebanon’s inclusion in the ceasefire is an ongoing matter of rivalry which additionally dangers upending the weekend’s talks.

Iran has repeatedly mentioned the ceasefire covers assaults towards its Lebanon-based proxy Hezbollah, echoing the stance of Pakistan, which helped dealer the deal. But Israel and the US have mentioned the ceasefire doesn’t embody Lebanon.

On Wednesday, simply hours after the ceasefire got here into impact, Israel launched its largest wave of strikes in Lebanon since the warfare started, pounding busy neighborhoods with out warning and killing a minimum of 303 folks and wounding greater than 1,000, in accordance to Lebanon’s well being ministry.

Smoke rises following several Israeli airstrikes in Beirut, Lebanon, Wednesday, April 8, 2026. (AP Photo/Hassan Ammar)

The assaults drew swift world backlash and ire from Iran. Ghalibaf, Iran’s parliament speaker, mentioned Thursday that Lebanon and Iran’s proxies type an “inseparable part of the ceasefire” and that “time is running out.”

Criticism of Israel additionally poured in from throughout the globe, together with from European and Gulf powers fearful that the ceasefire might unravel earlier than talks even begin.

Vance mentioned there had been a “legitimate misunderstanding” concerning Lebanon’s inclusion in the ceasefire. He additionally mentioned Israelis could “check themselves a little bit” with their ongoing strikes.

Reopening the important waterway, which has been successfully shuttered by Iran for weeks, wreaking havoc on world oil markets, was one other a part of the deal, in accordance to the White House.

But since the ceasefire, solely a handful of vessels have been ready to move by way of the chokepoint. Hundreds of vessels are nonetheless caught in the Persian Gulf with hundreds of crew on board.

Iran halted tanker visitors by way of the Strait of Hormuz after Israel attacked Lebanon, semi-official information company Fars reported. Iranian Parliament Speaker Mohammad Bagher Ghalibaf doubled down on that posture, saying that “ceasefire violations carry explicit costs and STRONG responses.”

Vance on Thursday reiterated that if Iran doesn’t comply with by way of on guarantees to reopen the Strait, the ceasefire will finish. Trump additionally warned Iran towards charging tolls to oil tankers in the key transport lane.

Boats overlooking the strait of Hormuz, in Musandam governance, in Oman, April 8, 2026.

Despite the confusion, American officers on Thursday have been shifting rapidly to put together for the negotiations, folks accustomed to the matter advised NCS.

If Iran chooses to withdraw, “that would be dumb but that’s their choice,” Vance mentioned.

Despite the disagreements, Trump advised NBC he was “very optimistic” about a peace deal out of this weekend’s talks in Islamabad, telling the outlet that Iran’s leaders appeared open to peace in non-public discussions.

“They’re much more reasonable,” he advised NBC. “They’re agreeing to all the things that they have to agree to. Remember, they’ve been conquered. They have no military.”

Iran’s public messaging is markedly completely different, with a number of state media shops claiming the nation has gained a powerful victory by surviving the US and Israel’s onslaught and bringing Washington to the desk.

And, even when the talks do go forward, it’s exhausting to say whether or not the gulf between the two sides might be bridged over a weekend in Pakistan.

According to sources accustomed to the ceasefire talks, the weekend assembly is anticipated to be the first of a number of intense negotiations concerning a long run, lasting deal to finish the warfare.



Sources

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