Napoli hope Kevin De Bruyne, Scott McTominay and Rasmus Hojlund can get them again on monitor, as Maurizio Sarri’s Lazio begin Mattia Zaccagni and Matteo Cancellieri.
It kicks off on the Stadio Diego Armando Maradona at 17.00 UK time (18.00 CEST).
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Napoli want a victory to keep up any slender hope of maintaining with leaders Inter, but additionally must look over their shoulders because the struggle for the highest 4 hots up after their 1-1 draw at Parma.
The absentee checklist stays in depth, together with Romelu Lukaku, Giovanni Di Lorenzo, David Neres and Antonio Vergara, however Amir Rrahmani returns to the bench.
PARMA, ITALY – APRIL 12: Scott McTominay of Napoli SSC reacts in the course of the Serie A match between Parma Calcio 1913 and SSC Napoli at Stadio Ennio Tardini on April 12, 2026 in Parma, Italy. (Photo by Emmanuele Ciancaglini/Getty Images)
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The ‘Fab Four’ of Stanislav Lobotka, Andre Frank Zambo Anguissa, De Bruyne and McTominay once more begin collectively in assist of the ever-present Hojlund.
Sam Beukema is chosen somewhat than Juan Jesus, who made expensive errors final week.
It is at all times a particular match for former Napoli coach Sarri, however he has if something even worse damage issues than Antonio Conte.
Adam Marusic is simply the most recent to hitch Ivan Provedel, Nicolò Rovella, Samuel Gigot and Alessio Furlanetto on the remedy desk, however Daniel Maldini does return for a spot on the bench.
Sarri has to look forward to Wednesday’s Coppa Italia semi-final in opposition to Atalanta, as the primary leg ended 2-2 final month, and it’s their final probability to salvage a traumatic season.
ROME, ITALY – FEBRUARY 15: Mattia Zaccagni of SS Lazio in motion in the course of the Serie A match between SS Lazio and Napoli at Stadio Olimpico on February 15, 2025 in Rome, Italy. (Photo by Marco Rosi – SS Lazio/Getty Images)
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After a number of video games utilized in midfield, Patric is rested, as Danilo Cataldi is approaching full health, however Mario Gila shakes off a knock to start out.
Zaccagni and Cancellieri flank Tijjani Noslin because the centre-forward, leaving Gustav Isaksen and Boulaye Dia on the bench.
It was a famously ill-tempered affair the final time these sides met, Napoli rising 2-0 winners with Noslin, Adam Marusic and Pasquale Mazzocchi despatched off.
ROME, ITALY – JANUARY 04: Adam Marusic of SS Lazio reacts wiith Antonio Conte and Pasquale Mazzocchi of SSC Napoli in the course of the Serie A match between SS Lazio and SSC Napoli at Stadio Olimpico on January 04, 2026 in Rome, Italy. (Photo by Marco Rosi – SS Lazio/Getty Images)
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Napoli vs. Lazio official line-ups
Napoli: Milinkovic-Savic; Beukema, Buongiorno, Olivera; Politano, Lobotka, Anguissa, Spinazzola; De Bruyne, McTominay; Hojlund
Lazio: Motta; Lazzari, Gila, Romagnoli, Nuno Tavares; Taylor, Cataldi, Basic; Cancellieri, Noslin, Zaccagni