Lions vs. Buccaneers 2025 Prediction, Odds, Picks – Oct 20

The Detroit Lions (4-2) are favored by 6.5 points against the Tampa Bay Buccaneers (5-1) on October 20, 2025, starting at 7 p.m. ET, airing on ABC/ESPN. The expected point total for the matchup is set at 53.5.

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Lions vs. Buccaneers Odds & Betting Lines

Lions vs. Buccaneers Prediction & Pick

• Pick ATS: Buccaneers (+6.5)
  
• Pick OU: Over (53.5)
  
• Prediction: Buccaneers 28 – Lions 26

How to Watch Detroit vs. Tampa Bay

• Game date: Monday, October 20, 2025
• Time: 7 p.m. ET
• Venue: Ford Field
• Location: Detroit, Michigan
• TV: ABC/ESPN
• Live Boxscore: FOX Sports

Lions vs. Buccaneers Recent Matchups

• Over their last five meetings, Detroit has collected three wins versus Tampa Bay.
• Tampa Bay has tallied 108 points in its last five tilts versus Detroit, mirroring the Lions’ offensive output (108 points) in those games.

Detroit Betting Info

• Against the spread, Detroit is 4-2-0 this year.
• The Lions have been favored by 6.5 points or more two times this season, and covered the spread in both.
• Detroit games in 2025 have hit the over three times in six opportunities (50%).
• The Lions have yet to lose a game they played as the moneyline favorite, going 3-0 in those matchups this season.
• The Lions have an implied win probability, based on the moneyline, of 74.0%.

Lions Stats

Detroit’s Key Players

Offense

• Jared Goff ranks 10th in the NFL with 1,390 passing yards in six games this year, averaging 231.7 per game with a 75.9% completion percentage and 14 touchdowns (first in the NFL) against two interceptions.
• Amon-Ra St. Brown’s 452 receiving yards this season (sixth in the NFL) have come from 51 targets and 44 receptions (fourth in the NFL). He’s averaging 75.3 receiving yards and 7.3 catches per game, with six receiving touchdowns (first in the NFL).
• Jahmyr Gibbs’ output on the ground this season includes 390 yards and four TDs. He’s averaging 65.0 yards per game and 4.5 per attempt (20th in the NFL).
• Gibbs has received 25 targets in the passing game and has 23 catches (3.8 per game) for 112 yards (18.7 per game) and one TD.
• In the ground game, David Montgomery averages 5.1 yards per attempt (10th in the NFL) and 55.7 yards per game for 334 total rushing yards. He has recorded four rushing touchdowns this season.
• He’s added nine catches (on 10 targets) for 78 receiving yards with zero touchdowns. He’s averaging 13.0 receiving yards and 1.5 receptions per game.

Defense

• On defense, Jack Campbell has 54 tackles, 3.0 TFL, and two sacks in 2025.
• Aidan Hutchinson has 6.0 sacks (fourth in the NFL) to go with 6.0 TFL and 14 tackles.
• Alex Anzalone has recorded 35 tackles, 1.0 TFL, 1.5 sacks, and one interception this year.
• This season, Derrick Barnes has 35 tackles, 2.0 TFL, and two sacks.

Tampa Bay Betting Info

• Tampa Bay has put together a record of 4-2-0 against the spread this season.
• Tampa Bay games have gone over the total four times this year.
• The Buccaneers have won two of the three games they’ve played as underdogs this season.
• The Buccaneers have a 30.3% chance to win this game based on the implied probability of the moneyline.

Buccaneers Stats

Tampa Bay’s Key Players

Offense

• Baker Mayfield is averaging 7.9 passing yards per attempt (eighth in the NFL) and 256.5 yards per game this year, completing 66.2% of his passes on the way to 1,539 total yards (fourth in the NFL), 12 touchdowns (fourth in the NFL) and one interception through six games.
• He’s added 158 yards on the ground (third on the Buccaneers), with zero rushing touchdowns. He’s averaging 26.3 yards per game and 7.2 per attempt.
• Emeka Egbuka has put together a 2025 campaign that includes 27 catches for 469 yards (fifth in the NFL) and five receiving touchdowns (third in the NFL) over six games played. He has been on the receiving end of 42 targets and is averaging 4.5 receptions per game.
• Rachaad White has rushed for four touchdowns this year, and has totaled 214 rushing yards (35.7 per game and 4.0 per carry).
• White’s offensive output includes 15 receptions (2.5 per game) on 16 targets for 85 yards (14.2 per game), though he has not scored a touchdown through the air.
• Bucky Irving has 237 rushing yards (leading the Buccaneers), without scoring a rushing touchdown, while averaging 59.3 yards per game and 3.3 per attempt (42nd in the NFL).
• Irving has also tacked on 19 catches (4.8 per game) for 193 yards (48.3 per game) and two receiving touchdowns. He has been on the receiving end of 19 targets.

Defense

• So far in 2025, Lavonte David has amassed 2.5 sacks to go with 5.0 TFL, 40 tackles, and one interception over six games.
• Tykee Smith has 1.0 sack (fifth on the Buccaneers) to go with 2.0 TFL and 45 tackles.
• SirVocea Dennis has 40 tackles, 5.0 TFL, and two passes defended in the 2025 season.
• Jacob Parrish has totaled 1.0 sack (fifth on the Buccaneers) as well as 3.0 TFL and 28 tackles.

FOX Sports created this story utilizing know-how supplied by Data Skrive and information from Sportradar.

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