From mannequin to molecule: Partnership combines pioneering AI for protein design with genomics experience to speed up growth of subsequent era enzymes

REDWOOD CITY, Calif. & EMERYVILLE, Calif.–(BUSINESS WIRE)–#AIIntegrated DNA Technologies (IDT), a Danaher firm and a world chief in genomics, and Profluent Bio, a pacesetter in AI-first protein design, have activated a strategic collaboration to design and optimize next-generation enzymes. The partnership brings collectively Profluent’s cutting-edge generative AI platform with IDT’s experience in enzymology and genomics, to discover new paths for creating novel enzyme variants. The collaboration additionally cements IDT’s not too long ago established innovation nexus within the Bay Area, signaling its continued dedication to pioneering synthesis applied sciences and fast-tracking development in oncology analysis.




“At IDT, we’ve built a strong enzyme engineering capability—innovating proprietary enzymes that have powered countless scientific breakthroughs,” mentioned IDT President Ajay Gannerkote. “This collaboration with Profluent Bio represents a bold step forward in our strategic roadmap. By integrating Profluent’s AI-driven protein design with IDT’s enzymology and genomics expertise, we will unearth new possibilities across a broad range of critical applications, from epigenetics to cancer research and beyond.”

Ali Madani, PhD, founder and CEO of Profluent Bio added, “Pairing Profluent’s AI with IDT’s world-class enzymology and manufacturing expertise is a powerful way to bring new capabilities to researchers and the industry. This partnership reflects our belief that AI-designed proteins can unlock step-changes in enzyme efficiency, precision, and manufacturability, without being constrained by what evolution has already tried.”

Profluent’s foundational fashions, together with the newest era ProGen3, are skilled on the Profluent Protein Atlas, a curated multibillion-sequence dataset that allows broad organic understanding and exact alignment with experimental information. These fashions have already demonstrated real-world impression by means of improvements like OpenCRISPR-1™, the world’s first AI-generated gene editor.

IDT will leverage its enzyme growth infrastructure, genomics experience, and international manufacturing footprint to take a look at, validate, and scale Profluent-designed sequences and gasoline its new product innovation pipeline. As an working firm of Danaher—which is investing throughout the enterprise in AI for molecular design—IDT is uniquely positioned to speed up the interpretation of AI-driven designs into high-performance, production-ready enzymes. This collaboration displays IDT’s dedication to advancing enzyme innovation, propels its innovation engine, and will increase customization of its novel enzymology capabilities to improve precision and pace of its bespoke subsequent era sequencing, artificial biology and gene enhancing choices.

By uniting Profluent’s AI-driven design with IDT’s experience, the partnership goals to streamline the trail from in silico designs to ready-to-use organic instruments—delivering pace, scale and scientific impression.

About Profluent Bio

Profluent is an AI-first firm pushing the frontier of de novo protein design to writer new biology. Grounded in nature with AI as an interpreter, Profluent’s highly effective basis mannequin platform unlocks options that remodel medication, agriculture, and past. Founded in 2022 and headquartered in Emeryville, CA, Profluent is backed by main buyers together with Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures. To be taught extra, go to profluent.bio or comply with the corporate on LinkedIn, X, and YouTube.

About IDT

Building from a robust basis of innovation, experience, and reliability, Integrated DNA Technologies (IDT) has developed from an oligo producer to a number one genomics supplier. We work shoulder-to-shoulder with scientific and international well being companions to allow genomics breakthroughs at scale. Our imaginative and prescient of enabling researchers to quickly transfer from the lab to life-changing advances displays our ongoing dedication to a more healthy, brighter future for all.

IDT is proud to be half of Danaher, a world science and know-how chief. Visit www.Danaher.com to be taught extra about Danaher, a number one life sciences and diagnostics innovator dedicated to accelerating the facility of science and know-how to enhance human well being.

For extra details about IDT, go to www.idtdna.com and comply with the corporate on LinkedIn, X, Facebook, YouTube, and Instagram.

Disclaimer: RUO — For analysis use solely. Not to be used in diagnostic procedures. Unless in any other case agreed to in writing, IDT doesn’t intend these merchandise to be utilized in scientific functions and doesn’t warrant their health or suitability for any scientific diagnostic use. Purchaser is solely answerable for all choices relating to the use of these merchandise and any related regulatory or authorized obligations.

Contacts

Integrated DNA Technologies
Kristina Sarenas

[email protected]
800-328-2661 (USA & Canada)

+1 319-626-8400 (outdoors USA)

Profluent Bio
Melvin Gruesbeck

Head of Communications

[email protected]





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