Insider Brief

  • The U.S. Department of Energy has introduced a $293 million Request for Application to help the Genesis Mission, inviting interdisciplinary groups to leverage AI fashions for addressing over 20 nationwide challenges together with quantum data science, superior manufacturing, biotechnology, important supplies, and nuclear vitality.
  • Phase I awards will vary from $500,000 to $750,000 for nine-month initiatives, whereas Phase II awards will vary from $6 million to $15 million over three years, with functions open to groups from DOE National Laboratories, U.S. business, and academia.
  • Phase I functions and Phase II letters of intent are due April 28, 2026, with Phase II functions due May 19, 2026, and an informational webinar scheduled for March 26, 2026, below funding alternative DE-FOA-0003612.
  • Photo from Pexels by Andrea Piacquadio.

PRESS RELEASE — The U.S. Department of Energy (DOE) at this time introduced funding to advance the Genesis Mission’s efforts to deal with the nation’s most advanced science and expertise challenges. This features a $293 million Request for Application (RFA),“The Genesis Mission: Transforming Science and Energy with AI.” Through this RFA, DOE invitations interdisciplinary groups to leverage novel AI fashions and frameworks to deal with over 20 nationwide challenges spanning superior manufacturing, biotechnology, important supplies, nuclear vitality, and quantum data science.   

“The Genesis Mission has caught the imagination of our scientific and engineering communities to tackle national challenges in the age of AI,” stated Under Secretary for Science Darío Gil and Genesis Mission Director. “With these investments we seek breakthrough ideas and novel collaborations leveraging the scientific prowess of our National Laboratories, the private sector, universities, and science philanthropies.” 

The RFA is open to interdisciplinary groups from DOE National Laboratories, U.S. business, and academia. Phase I awards will vary from $500,000 to $750,000 and will help a 9 month challenge interval. Phase II awards will vary from $6 million to $15 million over a 3 12 months challenge interval. Teams could apply on to both section in FY 2026, and profitable Phase I groups shall be eligible to compete for bigger Phase II awards in future cycles.

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Phase I functions and Phase II letters of intent are due April 28, 2026. Phase II functions are due May 19, 2026. DOE plans to carry an informational webinar about this RFA on March 26, 2026. 

For full eligibility, utility directions, and problem particulars, see the official NOFO: DE-FOA-0003612. Registration directions and different particulars shall be posted here



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