The NFL International Series continues in Week 1 of the 2025 season, with the Kansas City Chiefs taking over the Los Angeles Chargers in a renewal of this AFC West rivalry from São Paulo, Brazil. This marks the second regular-season sport to happen in South America, following last year’s game between the Philadelphia Eagles and the Green Bay Packers.

Kansas City is coming off its third consecutive journey to the Super Bowl after failing to three-peat in opposition to the Eagles in SBLIX. Patrick Mahomes and firm look to bounce again minus large receiver Rashee Rice, who will serve a six-game suspension, and All-Pro guard Joe Thuney, who was traded to Chicago within the offseason. All-Pro tight finish Travis Kelce and Hollywood Brown will stand as Mahomes’ prime targets out of the gate after WR Xavier Worthy was ruled out for the sport after injuring his shoulder on the opening drive.

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For the Chargers, it is about taking one other step ahead within the second 12 months of the Jim Harbaugh period. Offseason enhancements centered across the offense, particularly within the backfield. The Chargers drafted explosive RB Omarion Hampton out of North Carolina within the first spherical and signed veteran again Najee Harris in free company.

Justin Herbert’s second season in coach Harbaugh’s offense is one thing followers are eagerly anticipating, alongside with being reunited with Pro Bowl wideout Keenan Allen and second-year wideout Ladd McConkey, who had 82 receptions, 1,149 yards and seven touchdowns in his rookie marketing campaign.

Date: Friday, September 5

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Start time: 8 p.m. ET

Location: Corinthians Arena | São Paulo, Brazil

TV channel: YouTube

Follow alongside with Yahoo Sports for dwell updates, highlights and extra from the Chiefs-Chargers Week 1 matchup, kicking off the league’s 2025 NFL International Series:



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