Nate Tice & Charles McDonald dive into the Week 6 NFL slate with bold predictions, matchups to look at and extra. The two hosts kick issues off by getting Lost within the Sauce with their three favourite video games – San Francisco 49ers vs. Tampa Bay Buccaneers, Detroit Lions vs. Kansas City Chiefs & Chicago Bears vs. Washington Commanders – analyzing what to look at for on either side of the ball, key matchups and remaining predictions.

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Later, Nate & Charles bust out the Cheat Sheet, the place they every give one factor to look at within the Seattle Seahawks vs. Jacksonville Jaguars matchup and the Buffalo Bills taking over the Atlanta Falcons on Monday.

Finally, the duo give their Hail Mary bold predictions for the weekend, as Charles reluctantly backs the Cleveland Browns towards the Pittsburgh Steelers and Nate picks the New York Jets to tug off an enormous upset towards the Denver Broncos in London.

(2:40) – 49ers @ Buccaneers preview

(20:55) – Lions @ Chiefs preview

(39:15) – Bears @ Commanders preview

(52:30) – Cheat Sheet: SEA @ JAX and BUF @ ATL

(1:03:15) – Hail Mary bold predictions!

KANSAS CITY, MISSOURI - SEPTEMBER 28: Patrick Mahomes #15 of the Kansas City Chiefs reacts prior to an NFL football game against the Baltimore Ravens at GEHA Field at Arrowhead Stadium on September 28, 2025 in Kansas City, Missouri. (Photo by Michael Owens/Getty Images)

KANSAS CITY, MISSOURI – SEPTEMBER 28: Patrick Mahomes #15 of the Kansas City Chiefs reacts previous to an NFL soccer sport towards the Baltimore Ravens at GEHA Field at Arrowhead Stadium on September 28, 2025 in Kansas City, Missouri. (Photo by Michael Owens/Getty Images)

(Photo by Michael Owens/Getty Images)

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